At the LeoDerm Medical Center, photodynamic therapy is performed using the modern TREVIOLUX device, which ensures precision of action, control of parameters, and a high level of procedural safety. It is the combination of advanced technology and the doctors’ expertise that delivers predictable and aesthetically pleasing treatment results.

What is photodynamic therapy?

Photodynamic therapy (PDT) is a modern device-based skin treatment method that combines the action of special light radiation and active photosensitive components. Photodynamic treatment is recommended for patients with conditions such as actinic keratosis, Bowen’s disease, and superficial basal cell carcinomas.

How does photodynamic therapy work?

The principle of action and treatment is based on three components:

Photosensitizer — a light-sensitive substance (a special preparation) that is applied to the skin and accumulates in problematic cells.
Light radiation of a specific wavelength.
Oxygen in the tissues.

After activation by light, a photochemical reaction is triggered: reactive oxygen species are formed, which selectively destroy damaged or inflamed cells without harming healthy tissues. At the same time, collagen production is stimulated, microcirculation improves, and regeneration accelerates.

At the LeoDerm Medical Center, photodynamic therapy is performed using the modern TREVIOLUX device. This is a fractional laser system that allows precise control of the depth and intensity of exposure, ensuring safe stimulation and predictable treatment results. Thanks to the technological capabilities of the equipment and individualized parameter selection, photodynamic therapy can be adapted to the specific needs of each patient.

Photodynamic therapy is a method with clear medical indications. Before the procedure, the doctor always evaluates the patient’s condition, medical history, and possible limitations. It is important to understand that to achieve stable and predictable results, PDT is usually performed as a course — the number of procedures is determined individually depending on the diagnosis and clinical picture.

Indications for Photodynamic Therapy

PDT is effective in the treatment of a range of dermato-oncological conditions.

Photodynamic Therapy for Actinic Keratosis

Actinic keratosis is a precancerous skin lesion that develops as a result of prolonged exposure to ultraviolet radiation. Photodynamic therapy (PDT) allows for the targeted destruction of altered cells without damaging healthy tissues.

During the procedure, a photosensitizer — a special substance — is applied to the affected area, where it accumulates specifically in pathological cells. The area is then exposed to light of a specific wavelength. As a result, a photochemical reaction is triggered, leading to the destruction of atypical cells.

PDT effectively clears the skin of affected areas, reduces the risk of actinic keratosis progressing into skin cancer, and promotes tissue renewal.

Photodynamic Therapy for Bowen’s Disease

Bowen’s disease is a form of superficial squamous cell carcinoma of the skin (carcinoma in situ), in which pathological cells are located in the upper layers of the epidermis. One of the modern treatment methods is photodynamic therapy (PDT).

PDT allows for direct action on the affected cells. After applying a photosensitizer and subsequent light exposure, selective destruction of tumor cells occurs, while the surrounding healthy tissues remain largely unharmed.

This method is especially valuable for treating superficial lesions, as it does not require surgical intervention, helps preserve the aesthetic appearance of the skin, and reduces the risk of scarring.

Photodynamic Therapy for Basal Cell Carcinoma (Basalioma)

Basal cell carcinoma (basalioma) is one of the most common types of malignant skin tumors. At early stages, photodynamic therapy can be an effective treatment option.

During the procedure, the photosensitizer accumulates in the tumor cells. Upon activation by light, reactive oxygen species are generated, which destroy the cancer cells and disrupt their ability to grow further.

Photodynamic therapy allows for localized treatment of the tumor while preserving healthy tissues. The method is often used for superficial forms of basal cell carcinoma, especially on the face, where achieving both therapeutic and cosmetic results is important.

Contraindications for PDT

Despite its high safety profile, the procedure has certain limitations. Photodynamic therapy should not be performed in cases of:

pregnancy and breastfeeding;
individual hypersensitivity to photosensitizing agents;
systemic diseases in the decompensated stage;
acute infectious processes;
active inflammation or injuries in the treatment area;
severe forms of photosensitivity;
epilepsy.

Advantages of the Method

Photodynamic therapy primarily targets problem cells, minimizing the impact on healthy tissues. As a result, the skin recovers more gently, without aggressive damage. The TREVIOLUX equipment allows precise control over the depth and intensity of exposure, which increases safety, comfort, and predictability of results.

The decision on whether therapy is possible is made by the doctor during an in-person consultation. An individual assessment ensures that photodynamic therapy is as effective and safe as possible for the patient. If you are interested in the cost of photodynamic therapy or its applicability in your specific case, you can book a consultation with a dermatologist at the LeoDerm Medical Center in Lviv. During the first appointment, you will receive comprehensive information and a personalized photodynamic treatment plan to address your concerns.