Exosomes EXOXE

EXOXE exosomes have already gained recognition among doctors and patients for their effectiveness in rejuvenation programs, hair loss treatment, and skin rehabilitation after aggressive procedures. Exosomes in cosmetology are a combination of science, safety, and visible results.

What are exosomes?

Exosomes are microscopic extracellular vesicles (particles) secreted by living cells to transmit information to one another. They contain proteins, lipids, peptides, growth factors, RNA, and other bioactive molecules that act as “signal capsules.” Because of this, they can influence the function of recipient cells—activating repair processes, reducing inflammation, stimulating collagen and elastin synthesis, and improving tissue nourishment.

In medicine and cosmetology, exosomes are used for regeneration, accelerated healing, rejuvenation, and treatment of hair loss, as they trigger the body’s natural recovery mechanisms at the cellular level.

How do exosomes and active ingredients work?

The effectiveness of EXOXE exosomes has been confirmed by numerous modern studies. They have shown that exosomes for the face are an innovative technique for rejuvenation and regeneration:

• slow down cellular aging by blocking factors that accelerate degradation;
• activate tissue regeneration by stimulating cells responsible for creating new structures;
• increase collagen synthesis by up to 600% and elastin by up to 300%, restoring skin firmness and density;
• prevent photoaging and promote faster healing, reducing scar formation;
• decrease melanin production, helping to combat hyperpigmentation and even out skin tone.

In cosmetology, exosomes are actively used due to their powerful action at the cellular level:

1. Tissue regeneration. Exosomes keep cells in an active, healthy state, prevent age-related degeneration, and stimulate intensive collagen production, ensuring skin restoration and densification.
2. Inflammation modulation. Exosomes reduce the activity of immune cells in the damaged area, lowering inflammation and preventing tissue destruction.
3. Protection against photoaging. They neutralize UV-induced damage, maintain skin health, and preserve its youthful appearance.
4. Antioxidant effect. Exosomes decrease the levels of reactive oxygen species (ROS) that damage cells and regulate their life cycle, protecting against premature aging.
5. Angiogenesis. They stimulate the formation of new blood vessels, improving tissue nourishment and regeneration.
6. Regulation of cellular aging. Exosomes help keep cells young, slow down age-related changes, and maintain healthy cellular metabolism.

Such powerful action of EXOXE exosomes is explained by the composition of active ingredients:

• Exosomes (extracellular vesicles) from Lactobacillus paracasei – soothe, reduce signs of fatigue caused by external irritants, and help eliminate imperfections.
• Nidogen – one of the key proteins of the basal membrane; strengthens the structural foundation of the skin, improves its texture, and gives it radiance and elasticity.
• EGF (epidermal growth factor) – stimulates the growth of epidermal cells, maintains a healthy appearance, and restores the protective barrier.
• Collagen hydrolysate – a building material for skin restoration, improves its firmness and smoothness.
• Collagen (100,000) – strengthens the dermal framework, reduces wrinkles, and restores tissue density.
• Sodium hyaluronate – deeply moisturizes and retains moisture, enhancing firmness.
• Trehalose – a powerful antioxidant and moisturizer that protects against damage.

Exosomes are “signal capsules” that transmit biological information between cells. Their mechanism of action is as follows:

1. Recognize target cells thanks to specific proteins on their surface.
2. Penetrate the cell via endocytosis (particle absorption) or fusion with its membrane.
3. Release their contents—peptides, growth factors, RNA, and other bioactive substances.
4. Activate repair processes—triggering the synthesis of collagen, elastin, and hyaluronic acid, reducing inflammation, and regulating pigmentation.
5. Stimulate microcirculation—improving tissue nourishment and regeneration.

Protocols for EXOXE Application at LeoDerm Clinic

EXOXE + Microneedling (Dermapen)

How it works: The dermapen creates microchannels in the skin through which exosomes penetrate into the deeper layers. This increases their bioavailability many times over.

Why it is effective: The combination of micro-injuries and powerful restorative factors stimulates regeneration and enhances collagen and elastin synthesis.

Effects: Smoothing of wrinkles, improvement of skin texture, reduction of post-acne scars, and increased firmness.

EXOXE + RF (Radiofrequency Lifting)

How it works: RF heating stimulates collagen fiber contraction and triggers neocollagenesis. Exosomes enhance this process by providing cells with signals for faster recovery.

Why it is effective: Dual stimulation—thermal from RF and biological from exosomes.

Effects: Lifted facial contour, improved skin density, and reduced signs of aging.

EXOXE + Superficial Peeling

How it works: Peeling removes the stratum corneum, opening the way for exosome penetration. Active ingredients quickly reach the basal layer, where intensive regeneration occurs.

Why it is effective: The combination of exfoliation and cellular regeneration accelerates skin renewal.

Effects: Even skin tone, reduced pigmentation, tightened pores, smoothness, and radiance.

EXOXE + Laser Procedures

How it works: The laser causes controlled tissue damage, stimulating renewal. Exosomes significantly shorten recovery time and reduce the risk of complications.

Why it is effective: The laser activates regenerative processes, while exosomes provide essential signals and growth factors for rapid healing.

Effects: Shorter recovery period after laser treatment, improved firmness, smoother texture, and reduced wrinkles and scars.

Indications and Contraindications for Use

The exosome procedure for the face, body, and scalp is recommended by cosmetologists for addressing the following concerns:

• age-related skin changes—wrinkles, loss of firmness, etc.;
• enlarged pores;
• hyperpigmentation;
• scars, stretch marks;
• skin injuries and burns;
• acne during remission and post-acne;
• atopic dermatitis;
• alopecia.

Contraindications for the procedure include:

• pregnancy and breastfeeding;
• acute cardiovascular insufficiency and vascular pathologies;
• immunodeficiency;
• blood clotting disorders;
• oncology;
• skin diseases in the acute phase;
• acute infections.

Effectiveness

It is worth visiting LeoDerm Clinic in Lviv to learn more about how exosomes work for the face—the before and after results will impress you. EXOXE exosomes demonstrate high effectiveness by activating the skin’s natural regeneration and rejuvenation mechanisms. After a course of treatments, the skin becomes firmer, smoother, with an even tone and a noticeable healthy glow.